Lattice Models for Protein Organization throughout Thylakoid Membrane Stacks.

ABSTRACT: Proteins in photosynthetic membranes can organize into patterned arrays that span the membrane's lateral size. Attractions between proteins in different layers of a membrane stack can play a key role in this ordering, as was suggested by microscopy and fluorescence spectroscopy and demonstrated by computer simulations of a coarse-grained model. The architecture of thylakoid membranes, however, also provides opportunities for interlayer interactions that instead disfavor the high protein densities of ordered arrangements. Here, we explore the interplay between these opposing driving forces and, in particular, the phase transitions that emerge in the periodic geometry of stacked thylakoid membrane disks. We propose a lattice model that roughly accounts for proteins' attraction within a layer

SUBMITTER: Rosnik AM 

PROVIDER: S-EPMC7264851 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature