Ontology highlight
ABSTRACT:
SUBMITTER: McCleary S
PROVIDER: S-EPMC7265332 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
McCleary Stephen S Strong Rebecca R McCarthy Ronan R RR Edwards Jane C JC Howes Emma L EL Stevens Lisa M LM Sánchez-Cordón Pedro J PJ Núñez Alejandro A Watson Samantha S Mileham Alan J AJ Lillico Simon G SG Tait-Burkard Christine C Proudfoot Chris C Ballantyne Maeve M Whitelaw C Bruce A CBA Steinbach Falko F Crooke Helen R HR
Scientific reports 20200602 1
African swine fever virus (ASFV) causes a lethal, haemorrhagic disease in domestic swine that threatens pig production across the globe. Unlike domestic pigs, warthogs, which are wildlife hosts of the virus, do not succumb to the lethal effects of infection. There are three amino acid differences between the sequence of the warthog and domestic pig RELA protein; a subunit of the NF-κB transcription factor that plays a key role in regulating the immune response to infections. Domestic pigs with a ...[more]