Assessment of hemostatic profile in patients with mild to advanced liver cirrhosis.

ABSTRACT:

Background

Hemostasis of patients suffering from liver cirrhosis is challenging due to both, pro- and anticoagulatory disorders leading to hemostatic alterations with distinct abnormalities of coagulation. Pathological changes in conventional coagulation analysis and platelet count are common manifestations of decreased liver synthesis of coagulation factors and reduced platelet count in these patients. However, conventional coagulation analysis and platelet count do not reflect in-vivo coagulation status or platelet function. The purpose of this present observational study was therefore to assess the haemostatic profile including plasmatic coagulation using thrombelastometry and impedance aggregometry for platelet function in patients suffering from liver cirrhosis.

Aim

To

SUBMITTER: Adam EH 

PROVIDER: S-EPMC7267688 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature