Ontology highlight
ABSTRACT:
SUBMITTER: Falgas N
PROVIDER: S-EPMC7267898 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Falgàs Neus N Ruiz-Peris Mariona M Pérez-Millan Agnès A Sala-Llonch Roser R Antonell Anna A Balasa Mircea M Borrego-Écija Sergi S Ramos-Campoy Oscar O Augé Josep Maria JM Castellví Magdalena M Tort-Merino Adrià A Olives Jaume J Fernández-Villullas Guadalupe G Blennow Kaj K Zetterberg Henrik H Bargalló Núria N Lladó Albert A Sánchez-Valle Raquel R
Human brain mapping 20200116 8
Prior studies have described distinct patterns of brain gray matter and white matter alterations in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD), as well as differences in their cerebrospinal fluid (CSF) biomarkers profiles. We aim to investigate the relationship between early-onset AD (EOAD) and FTLD structural alterations and CSF biomarker levels. We included 138 subjects (64 EOAD, 26 FTLD, and 48 controls), all of them with a 3T MRI brain scan and CSF biomarkers avail ...[more]