Self-regulation of ventromedial prefrontal cortex activation using real-time fMRI neurofeedback-Influence of default mode network.

ABSTRACT: The ventromedial prefrontal cortex (vmPFC) is involved in regulation of negative emotion and decision-making, emotional and behavioral control, and active resilient coping. This pilot study examined the feasibility of training healthy subjects (n = 27) to self-regulate the vmPFC activity using a real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf). Participants in the experimental group (EG, n = 18) were provided with an ongoing vmPFC hemodynamic activity (rtfMRI-nf signal represented as variable-height bar). Individuals were instructed to raise the bar by self-relevant value-based thinking. Participants in the control group (CG, n = 9) performed the same task; however, they were provided with computer-generated sham neurofeedback signal. Results demonstrate that (a) b

SUBMITTER: Mayeli A 

PROVIDER: S-EPMC7267960 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature