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Education in the genomics era: Generating high-quality genome assemblies in university courses.


ABSTRACT: Recent advances in genome sequencing technologies have simplified the generation of genome data and reduced the costs for genome assemblies, even for complex genomes like those of vertebrates. More practically oriented genomic courses can prepare university students for the increasing importance of genomic data used in biological and medical research. Low-cost third-generation sequencing technology, along with publicly available data, can be used to teach students how to process genomic data, assemble full chromosome-level genomes, and publish the results in peer-reviewed journals, or preprint servers. Here we outline experiences gained from 2 master's-level courses and discuss practical considerations for teaching hands-on genome assembly courses.

SUBMITTER: Prost S 

PROVIDER: S-EPMC7268781 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Education in the genomics era: Generating high-quality genome assemblies in university courses.

Prost Stefan S   Winter Sven S   De Raad Jordi J   Coimbra Raphael T F RTF   Wolf Magnus M   Nilsson Maria A MA   Petersen Malte M   Gupta Deepak K DK   Schell Tilman T   Lammers Fritjof F   Janke Axel A  

GigaScience 20200601 6


Recent advances in genome sequencing technologies have simplified the generation of genome data and reduced the costs for genome assemblies, even for complex genomes like those of vertebrates. More practically oriented genomic courses can prepare university students for the increasing importance of genomic data used in biological and medical research. Low-cost third-generation sequencing technology, along with publicly available data, can be used to teach students how to process genomic data, as  ...[more]

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