Ontology highlight
ABSTRACT:
SUBMITTER: Benayas B
PROVIDER: S-EPMC7271138 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Benayas Beatriz B Sastre Isabel I López-Martín Soraya S Oo Adrian A Kim Baek B Bullido Maria J MJ Aldudo Jesús J Yáñez-Mó María M
Medical microbiology and immunology 20200604 4
Different members of the tetraspanin superfamily have been described to regulate different virus infectious cycles at several stages: viral entry, viral replication or virion exit or infectivity. In addition, tetraspanin CD81 regulates HIV reverse transcription through its association with the dNTP hydrolase SAMHD1. Here we aimed at analysing the role of CD81 in Herpes simplex virus 1 infectivity using a neuroblastoma cell model. For this purpose, we generated a CD81 KO cell line using the CRISP ...[more]