Ontology highlight
ABSTRACT:
SUBMITTER: Ostuni MA
PROVIDER: S-EPMC7271195 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Ostuni Mariano A MA Hermand Patricia P Saindoy Emeline E Guillou Noëlline N Guellec Julie J Coens Audrey A Hattab Claude C Desuzinges-Mandon Elodie E Jawhari Anass A Iatmanen-Harbi Soria S Lequin Olivier O Fuchs Patrick P Lacapere Jean-Jacques JJ Combadière Christophe C Pincet Frédéric F Deterre Philippe P
Scientific reports 20200603 1
During inflammatory response, blood leukocytes adhere to the endothelium. This process involves numerous adhesion molecules, including a transmembrane chemokine, CX3CL1, which behaves as a molecular cluster. How this cluster assembles and whether this association has a functional role remain unknown. The analysis of CX3CL1 clusters using native electrophoresis and single molecule fluorescence kinetics shows that CX3CL1 is a homo-oligomer of 3 to 7 monomers. Fluorescence recovery after photobleac ...[more]