Ontology highlight
ABSTRACT:
SUBMITTER: Ma Q
PROVIDER: S-EPMC7273445 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Ma Quanfeng Q Wang Xiuyu X Wang Hong H Song Wen W Wang Qiong Q Wang Jinhuan J
BioMed research international 20200521
HMGN5 regulates biological function and molecular transcription via combining with a nucleosome. There has been growing evidence that aberrant expression of HMGN5 is associated with malignant neoplasm development and progression. In the present study, we found that the expression of HMGN5 is significantly higher in high-grade glioblastoma tissues than in low-grade samples. To clarify the function of HMGN5 in glioblastoma, we knocked down HMGN5 in U87 and U251 glioblastoma cells via siRNA. The re ...[more]