Ontology highlight
ABSTRACT:
SUBMITTER: Jiang J
PROVIDER: S-EPMC7274031 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Jiang Junjun J Hu Xi X Li Wenwei W Liu Jie J Liang Bingyu B Chen Hui H Huang Jiegang J Zang Ning N Ning Chuanyi C Liao Yanyan Y Chen Rongfeng R Lai Jingzhen J Chu Jiemei J Pan Peijiang P Cui Ping P Tang Qiao Q Chen Xiu X Liang Hao H Ye Li L
Frontiers in immunology 20200529
Innate immunity is the first line of defense against invading pathogens and may mediate HIV-1 resistance in HIV-1-exposed seronegative (HESN) individuals. This study aims to identify components of innate immunity that confer natural HIV-1 resistance in Chinese HESN individuals. Specifically, we compared the expression levels of Toll-like receptors (TLRs) and associated pathway molecules in peripheral blood mononuclear cells (PBMCs), monocytes/macrophages, and plasma obtained from HESN and contro ...[more]