Ontology highlight
ABSTRACT:
SUBMITTER: Xu X
PROVIDER: S-EPMC7274780 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
eLife 20200527
The oxaloacetate decarboxylase sodium pump (OAD) is a unique primary-active transporter that utilizes the free energy derived from oxaloacetate decarboxylation for sodium transport across the cell membrane. It is composed of 3 subunits: the α subunit catalyzes carboxyl-transfer from oxaloacetate to biotin, the membrane integrated β subunit catalyzes the subsequent carboxyl-biotin decarboxylation and the coupled sodium transport, the γ subunit interacts with the α and β subunits and stabilizes th ...[more]