Ontology highlight
ABSTRACT:
SUBMITTER: Ishak M
PROVIDER: S-EPMC7277229 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Ishak Muhiddin M Baharudin Rashidah R Rose Isa Mohamed IM Sagap Ismail I Mazlan Luqman L Azman Zairul Azwan Mohd ZAM Abu Nadiah N Jamal Rahman R Lee Learn-Han LH Mutalib Nurul Syakima Ab NSA
Biomolecules 20200505 5
The methylome of open chromatins was investigated in colorectal cancer (CRC) to explore cancer-specific methylation and potential biomarkers. Epigenome-wide methylome of open chromatins was studied in colorectal cancer tissues using the Infinium DNA MethylationEPIC assay. Differentially methylated regions were identified using the ChAMP Bioconductor. Our stringent analysis led to the discovery of 2187 significant differentially methylated open chromatins in CRCs. More hypomethylated probes were ...[more]