Ontology highlight
ABSTRACT:
SUBMITTER: Koustas E
PROVIDER: S-EPMC7277892 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Koustas Evangelos E Sarantis Panagiotis P Papavassiliou Athanasios G AG Karamouzis Michalis V MV
Biomolecules 20200425 5
The emergence of cancer immunotherapy has already shown some remarkable results, having changed the treatment strategy in clinical practice for solid tumors. Despite these promising long-term responses, patients seem to lack the ability to respond to immune checkpoint inhibitors, thus demonstrating a primary resistance to immunotherapy. Moreover, a significant number of patients who initially respond to treatment eventually acquire resistance to immunotherapy. Both resistance mechanisms are a re ...[more]