Ontology highlight
ABSTRACT:
SUBMITTER: Taverna S
PROVIDER: S-EPMC7278927 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Taverna Simona S Giusti Ilaria I D'Ascenzo Sandra S Pizzorno Laura L Dolo Vincenza V
International journal of molecular sciences 20200518 10
Cancer incidence and mortality are rapidly growing worldwide. The main risk factors for cancer can be associated with aging as well as the growth of the population and socioeconomic condition. Breast cancer, a crucial public health problem, is the second cause of death among women. About 70% of patients with advanced breast cancer have bone metastases. In bone metastasis, cancer cells and osteoclasts form a vicious cycle: cancer cells promote osteoclast differentiation and activation that, in tu ...[more]