Ontology highlight
ABSTRACT:
SUBMITTER: Yamaguchi M
PROVIDER: S-EPMC7278983 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Yamaguchi Maki M Kimura Masako M Ohno Tetsuo T Nakahara Naoya N Akiyama Nobutake N Takemori Shigeru S Yagi Naoto N
International journal of molecular sciences 20200515 10
X-ray diffraction and tension measurement experiments were conducted on rat left ventricular skinned fibers with or without "troponin-T treatment," which exchanges the endogenous troponin T/I/C complex with exogenous troponin-T. These experiments were performed to observe the structural changes in troponin-T within a fiber elicited by contractile crossbridge formation and investigate the abnormality of hypertrophic cardiomyopathy-related troponin-T mutants. The intensity of the troponin reflecti ...[more]