Ontology highlight
ABSTRACT:
SUBMITTER: Kim DW
PROVIDER: S-EPMC7279008 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Kim Dae-Won DW Jo You-Young YY Garagiola Umberto U Choi Je-Yong JY Kang Yei-Jin YJ Oh Ji-Hyeon JH Kim Seong-Gon SG
International journal of molecular sciences 20200514 10
4-Hexyl resorcinol (4HR) is an organic compound and has been used in skin care application. 4HR is an M2-type macrophage activator and elevates vascular endothelial growth factor (VEGF) expression via the hypoxia-inducible factor (HIF)-independent pathway. As endothelial cells are important in wound healing, the human umbilical vein endothelial cells (HUVECs) were treated with 4HR, and changes in VEGF-A, -C, and transforming growth factor-β1 (TGF-β1) expression were investigated. The administrat ...[more]