Ontology highlight
ABSTRACT:
SUBMITTER: Federico A
PROVIDER: S-EPMC7279140 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Federico Antonio A Serra Angela A Ha My Kieu MK Kohonen Pekka P Choi Jang-Sik JS Liampa Irene I Nymark Penny P Sanabria Natasha N Cattelani Luca L Fratello Michele M Kinaret Pia Anneli Sofia PAS Jagiello Karolina K Puzyn Tomasz T Melagraki Georgia G Gulumian Mary M Afantitis Antreas A Sarimveis Haralambos H Yoon Tae-Hyun TH Grafström Roland R Greco Dario D
Nanomaterials (Basel, Switzerland) 20200508 5
Preprocessing of transcriptomics data plays a pivotal role in the development of toxicogenomics-driven tools for chemical toxicity assessment. The generation and exploitation of large volumes of molecular profiles, following an appropriate experimental design, allows the employment of toxicogenomics (TGx) approaches for a thorough characterisation of the mechanism of action (MOA) of different compounds. To date, a plethora of data preprocessing methodologies have been suggested. However, in most ...[more]