Ontology highlight
ABSTRACT:
SUBMITTER: Gunasekaran P
PROVIDER: S-EPMC7279249 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200520 10
To combat the escalating rise of antibacterial resistance, the development of antimicrobial peptides (AMPs) with a unique mode of action is considered an attractive strategy. However, proteolytic degradation of AMPs remains the greatest challenge in their transformation into therapeutics. Herein, we synthesized Fmoc-triazine amino acids that differ from each other by anchoring either cationic or hydrophobic residues. These unnatural amino acids were adopted for solid-phase peptide synthesis (SPP ...[more]