Unknown

Dataset Information

0

A Bird's-Eye View of Cell Sources for Cell-Based Therapies in Blood Cancers.


ABSTRACT: : Hematological malignancies comprise over a hundred different types of cancers and account for around 6.5% of all cancers. Despite the significant improvements in diagnosis and treatment, many of those cancers remain incurable. In recent years, cancer cell-based therapy has become a promising approach to treat those incurable hematological malignancies with striking results in different clinical trials. The most investigated, and the one that has advanced the most, is the cell-based therapy with T lymphocytes modified with chimeric antigen receptors. Those promising initial results prepared the ground to explore other cell-based therapies to treat patients with blood cancer. In this review, we want to provide an overview of the different types of cell-based therapies in blood cancer, describing them according to the cell source.

SUBMITTER: Motais B 

PROVIDER: S-EPMC7281611 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

altmetric image

Publications


<b>:</b> Hematological malignancies comprise over a hundred different types of cancers and account for around 6.5% of all cancers. Despite the significant improvements in diagnosis and treatment, many of those cancers remain incurable. In recent years, cancer cell-based therapy has become a promising approach to treat those incurable hematological malignancies with striking results in different clinical trials. The most investigated, and the one that has advanced the most, is the cell-based ther  ...[more]

Similar Datasets

| S-EPMC7494605 | biostudies-literature
| S-EPMC2639543 | biostudies-literature
| S-EPMC10886771 | biostudies-literature
| S-EPMC7080768 | biostudies-literature
| S-EPMC7717972 | biostudies-literature
| S-EPMC8276247 | biostudies-literature
| S-EPMC3590202 | biostudies-literature
| S-EPMC8079999 | biostudies-literature
| S-EPMC7647282 | biostudies-literature
| S-EPMC3208862 | biostudies-literature