Clinicopathological and prognostic significance and molecular mechanisms governing uveal melanoma.
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ABSTRACT:
SUBMITTER: Wu MY
PROVIDER: S-EPMC7281640 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Clinicopathological and prognostic significance and molecular mechanisms governing uveal melanoma.
Wu Meng-Yu MY Lai Tzu-Ting TT Liao Wan-Ting WT Li Chia-Jung CJ
Therapeutic advances in medical oncology 20200608
Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Although UM and cutaneous melanoma are derived from melanocytes, UM differs clinically and biologically from its more common skin counterparts. More than half of primary UMs metastasize. However, there is currently no effective treatment for metastatic UM. Therefore, studying mutations related to the metastasis, growth, proliferation, and survival of UM can help researchers understand its pathogenesis and metastatic ...[more]
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