Ontology highlight
ABSTRACT:
SUBMITTER: Arndt C
PROVIDER: S-EPMC7281723 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Arndt Claudia C Fasslrinner Frederick F Loureiro Liliana R LR Koristka Stefanie S Feldmann Anja A Bachmann Michael M
Cancers 20200521 5
The success of conventional chimeric antigen receptor (CAR) therapy in the treatment of refractory hematologic malignancies has triggered the development of novel exciting experimental CAR technologies. Among them, adaptor CAR platforms have received much attention. They combine the flexibility and controllability of recombinant antibodies with the power of CARs. Due to their modular design, adaptor CAR systems propose answers to the central problems of conventional CAR therapy, such as safety a ...[more]