Ontology highlight
ABSTRACT:
SUBMITTER: Floege J
PROVIDER: S-EPMC7282824 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20200601 6
<h4>Background</h4>The iron-based phosphate binders, sucroferric oxyhydroxide (SFOH) and ferric citrate (FC), effectively lower serum phosphorus in clinical studies, but gastrointestinal iron absorption from these agents appears to differ. We compared iron uptake and tissue accumulation during treatment with SFOH or FC using experimental rat models.<h4>Methods</h4>Iron uptake was evaluated during an 8-h period following oral administration of SFOH, FC, ferrous sulphate (oral iron supplement) or ...[more]