Ontology highlight
ABSTRACT:
SUBMITTER: Knudsen AM
PROVIDER: S-EPMC7283475 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Knudsen Arnon Møldrup AM Eilertsen Ida I Kielland Susanne S Pedersen Mikkel Warming MW Sørensen Mia Dahl MD Dahlrot Rikke Hedegaard RH Boldt Henning Bünsow HB Munthe Sune S Poulsen Frantz Rom FR Kristensen Bjarne Winther BW
Scientific reports 20200609 1
Most glioblastoma patients have a dismal prognosis, although some survive several years. However, only few biomarkers are available to predict the disease course. EGR1 and EGR3 have been linked to glioblastoma stemness and tumour progression, and this study aimed to investigate their spatial expression and prognostic value in gliomas. Overall 207 gliomas including 190 glioblastomas were EGR1/EGR3 immunostained and quantified. A cohort of 21 glioblastomas with high P53 expression and available ti ...[more]