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Novel coronavirus and regular physical activity involvement: Opinion.

ABSTRACT: The novel coronavirus (NCOVID-19) has quickly become a public health concern globally and needs urgent attention. While there is no current evidence of vaccines and specific drugs to prevent and treat the ailments emanating from NCOVID-19 infections, complementary and conventional medical treatments could prove beneficial in ameliorating some of the respiratory difficulties, especially in countries in sub-Saharan Africa. These treatments include specific breathing exercises, a diet that strengthens the immune system, as well as avoiding tobacco smoking and alcohol consumption. On the other hand, for those who have not contracted the virus, participation in indoor and within-the-yard physical activity could be beneficial in preventing unwanted weight gain as well as associated conditions such as anxiety and depression.

SUBMITTER: Onagbiye SO

PROVIDER: S-EPMC7284152 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Novel coronavirus and regular physical activity involvement: Opinion.

Onagbiye Sunday O SO Mchiza Zandile J R ZJR Bassett Susan H SH Travill Andre A Eijnde Bert O BO

African journal of primary health care & family medicine 20200521 1

The novel coronavirus (NCOVID-19) has quickly become a public health concern globally and needs urgent attention. While there is no current evidence of vaccines and specific drugs to prevent and treat the ailments emanating from NCOVID-19 infections, complementary and conventional medical treatments could prove beneficial in ameliorating some of the respiratory difficulties, especially in countries in sub-Saharan Africa. These treatments include specific breathing exercises, a diet that strength ...[more]

PMID: 32501017

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2016-04-05 | E-GEOD-79894 | biostudies-arrayexpress

Influence of regular physical activity on warfarin dose and risk of hemorrhagic complications.

Project description:OBJECTIVE:To determine the influence of regular physical activity on stable warfarin dose and risk of major hemorrhage in patients on chronic anticoagulation therapy. DESIGN:Regular physical activity (maintained over > 80% of visits) was ascertained by self-report at initiation of warfarin therapy (target international normalized ratio [INR] = 2-3) in 1272 patients, with changes documented at monthly anticoagulation clinic visits in a population-based prospective cohort. Multi-variable linear regression and survival analysis, respectively, were used to assess influence on warfarin and risk of hemorrhage. SETTING:Outpatient anticoagulation clinic PARTICIPANTS:1272 anticoagulated patients MEASUREMENT AND MAIN RESULTS:There were 683 (53.7%) patients who were regularly physically active (? 30 min ? 3 times/week). Physically active patients required warfarin doses that were 6.9% higher (p=0.006) than in physically inactive patients after controlling for sociodemographic factors, vitamin K intake, clinical factors, and genetic variations.The overall incidence of major hemorrhagic events was 7.6/100 person-years (p-yrs, 95% confidence interval [CI] 6.4-8.9) in our population. The incidence was lower for physically active patients (5.6/100 p-yrs, 95% CI 4.2-7.2) than in inactive patients (10.3/100 p-yrs, 95% CI 8.2-12.9, p=0.0004). Active patients had a 38% lower risk of hemorrhage (hazard ratio 0.62, 95% CI 0.42-0.98, p=0.03) compared with inactive patients. CONCLUSIONS:Regular physical activity is associated with higher warfarin dose requirements and lower risk of hemorrhage. The influence of physical activity on drug response needs to be further explored, and the mechanisms through which it exerts these effects need to be elucidated

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Regular physical activity followed by detraining increases the sensitivity of global gene expression to acute exercise stress

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| S-EPMC6594642 | biostudies-literature

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