Dataset Information

Variability of Coordination in Typically Developing Children Versus Children with Autism Spectrum Disorder with and without Rhythmic Signal.

ABSTRACT: Motor coordination deficit is a cardinal feature of autism spectrum disorder (ASD). Theevaluation of coordination of children with ASD is either lengthy, subjective (via observationalanalysis), or requires cumbersome post analysis. We therefore aimed to use tri-axial accelerometersto compare inter-limb coordination measures between typically developed (TD) children and childrenASD, while jumping with and without a rhythmic signal. Children aged 5-6 years were recruited tothe ASD group (n = 9) and the TD group (n = 19). Four sensors were strapped to their ankles and wristand they performed at least eight consecutive jumping jacks twice: at a self-selected rhythm and witha metronome. The primary outcome measures were the timing lag (TL), the timing difference of themaximal acceleration of the left and right limbs, and the lag variability (LV), the variation of TL acrossthe 5 jumps. The LV of the legs of children with ASD was higher compared to the LV of the legs of TDchildren during self-selected rhythm jumping (p < 0.01). Additionally, the LV of the arms of childrenwith ASD, jumping with the rhythmic signal, was higher compared to that of the TD children (p <0.05). There were no between-group differences in the TL parameter. Our preliminary findingssuggest that the simple protocol presented in this study might allow an objective and accuratequantification of the intra-subject variability of children with ASD via actigraphy.

SUBMITTER: Gabis LV

PROVIDER: S-EPMC7284634 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Variability of Coordination in Typically Developing Children Versus Children with Autism Spectrum Disorder with and without Rhythmic Signal.

Gabis Lidia V LV Shefer Shahar S Portnoy Sigal S

Sensors (Basel, Switzerland) 20200513 10

Motor coordination deficit is a cardinal feature of autism spectrum disorder (ASD). Theevaluation of coordination of children with ASD is either lengthy, subjective (via observationalanalysis), or requires cumbersome post analysis. We therefore aimed to use tri-axial accelerometersto compare inter-limb coordination measures between typically developed (TD) children and childrenASD, while jumping with and without a rhythmic signal. Children aged 5-6 years were recruited tothe ASD group (n = 9) an ...[more]

PMID: 32414059

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Project description:BackgroundBiological motion imparts rich information related to the movement, actions, intentions and affective state of others, which can provide foundational support for various aspects of social cognition and behavior. Given that atypical social communication and cognition are hallmark symptoms of autism spectrum disorder (ASD), many have theorized that a potential source of this deficit may lie in dysfunctional neural mechanisms of biological motion processing. Synthesis of existing literature provides some support for biological motion processing deficits in autism spectrum disorder, although high study heterogeneity and inconsistent findings complicate interpretation. Here, we attempted to reconcile some of this residual controversy by investigating a possible modulating role for attention in biological motion processing in ASD.MethodsWe employed high-density electroencephalographic recordings while participants observed point-light displays of upright, inverted and scrambled biological motion under two task conditions to explore spatiotemporal dynamics of intentional and unintentional biological motion processing in children and adolescents with ASD (n = 27), comparing them to a control cohort of neurotypical (NT) participants (n = 35).ResultsBehaviorally, ASD participants were able to discriminate biological motion with similar accuracy to NT controls. However, electrophysiologic investigation revealed reduced automatic selective processing of upright biologic versus scrambled motion stimuli in ASD relative to NT individuals, which was ameliorated when task demands required explicit attention to biological motion. Additionally, we observed distinctive patterns of covariance between visual potentials evoked by biological motion and functional social ability, such that Vineland Adaptive Behavior Scale-Socialization domain scores were differentially associated with biological motion processing in the N1 period in the ASD but not the NT group.LimitationsThe cross-sectional design of this study does not allow us to definitively answer the question of whether developmental differences in attention to biological motion cause disruption in social communication, and the sample was limited to children with average or above cognitive ability.ConclusionsTogether, these data suggest that individuals with ASD are able to discriminate, with explicit attention, biological from non-biological motion but demonstrate diminished automatic neural specificity for biological motion processing, which may have cascading implications for the development of higher-order social cognition.

Dataset Information

Variability of Coordination in Typically Developing Children Versus Children with Autism Spectrum Disorder with and without Rhythmic Signal.

Publications

Variability of Coordination in Typically Developing Children Versus Children with Autism Spectrum Disorder with and without Rhythmic Signal.

Similar Datasets

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