Ontology highlight
ABSTRACT:
SUBMITTER: Pla D
PROVIDER: S-EPMC7286001 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Pla Davinia D Rodríguez Yania Y Resiere Dabor D Mehdaoui Hossein H Gutiérrez José María JM Calvete Juan J JJ
Toxicon: X 20181229
<i>Bothrops lanceolatus</i> inflicts severe envenomings in the Lesser Caribbean island of Martinique. Bothrofav®, a monospecific antivenom against <i>B. lanceolatus</i> venom, has proven highly effective at the preclinical and clinical levels. Here, we report a detailed third-generation antivenomics quantitative analysis of Bothrofav®. With the exception of poorly-immunogenic peptides, Bothrofav® immunocaptured all the major protein components. These results, along with previous preclinical and ...[more]