Ontology highlight
ABSTRACT:
SUBMITTER: Johnson RJ
PROVIDER: S-EPMC7286363 | biostudies-literature | 2018 Jun
REPOSITORIES: biostudies-literature
Johnson Richard J RJ Bakris George L GL Borghi Claudio C Chonchol Michel B MB Feldman David D Lanaspa Miguel A MA Merriman Tony R TR Moe Orson W OW Mount David B DB Sanchez Lozada Laura Gabriella LG Stahl Eli E Weiner Daniel E DE Chertow Glenn M GM
American journal of kidney diseases : the official journal of the National Kidney Foundation 20180227 6
Urate is a cause of gout, kidney stones, and acute kidney injury from tumor lysis syndrome, but its relationship to kidney disease, cardiovascular disease, and diabetes remains controversial. A scientific workshop organized by the National Kidney Foundation was held in September 2016 to review current evidence. Cell culture studies and animal models suggest that elevated serum urate concentrations can contribute to kidney disease, hypertension, and metabolic syndrome. Epidemiologic evidence also ...[more]