Ontology highlight
ABSTRACT:
SUBMITTER: Riquelme E
PROVIDER: S-EPMC7288240 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Cell 20190801 4
Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor microbiota and the immune system in influencing long-term survival. Using 16S rRNA gene sequencing, we analyzed the tumor microbiome composition in PDAC patients with short-term survival (STS) and long-term survival (LTS). We found higher alpha-diversity in the tumor microbiome of LTS patients and identified an intra-tumoral ...[more]