Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Peinado N
PROVIDER: S-EPMC7288428 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Martinez-Peinado Nieves N Cortes-Serra Nuria N Torras-Claveria Laura L Pinazo Maria-Jesus MJ Gascon Joaquim J Bastida Jaume J Alonso-Padilla Julio J
Parasites & vectors 20200610 1
<h4>Background</h4>Chagas disease, caused by the protozoan Trypanosoma cruzi, is a neglected disease that affects ~7 million people worldwide. Development of new drugs to treat the infection remains a priority since those currently available have frequent side effects and limited efficacy at the chronic stage. Natural products provide a pool of diversity structures to lead the chemical synthesis of novel molecules for this purpose. Herein we analyzed the anti-T. cruzi activity of nine alkaloids ...[more]