Ontology highlight
ABSTRACT:
SUBMITTER: Agapito Fonseca J
PROVIDER: S-EPMC7290350 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Agapito Fonseca José J Gameiro Joana J Marques Filipe F Lopes José António JA
Journal of clinical medicine 20200510 5
Sepsis-associated acute kidney injury (SA-AKI) is a major issue in medical, surgical and intensive care settings and is an independent risk factor for increased mortality, as well as hospital length of stay and cost. SA-AKI encompasses a proper pathophysiology where renal and systemic inflammation play an essential role, surpassing the classic concept of acute tubular necrosis. No specific treatment has been defined yet, and renal replacement therapy (RRT) remains the cornerstone supportive ther ...[more]