Ontology highlight
ABSTRACT:
SUBMITTER: Andreata-Santos R
PROVIDER: S-EPMC7290698 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Andreata-Santos Robert R Alves Rúbens Prince Dos Santos RPDS Pereira Sara Araujo SA Pereira Lennon Ramos LR Freitas Carla Longo de CL Pereira Samuel Santos SS Venceslau-Carvalho Alexia Adrianne AA Castro-Amarante Maria Fernanda MF Favaro Marianna Teixeira Pinho MTP Mathias-Santos Camila C Amorim Jaime Henrique JH Ferreira Luís Carlos de Souza LCS
Viruses 20200506 5
In the present study, we evaluated the immunological responses induced by dengue vaccines under experimental conditions after delivery via a transcutaneous (TC) route. Vaccines against type 2 Dengue virus particles (DENV2 New Guinea C (NGC) strain) combined with enterotoxigenic <i>Escherichia coli</i> (ETEC) heat-labile toxin (LT) were administered to BALB/c mice in a three-dose immunization regimen via the TC route. As a control for the parenteral administration route, other mouse groups were i ...[more]