Ontology highlight
ABSTRACT:
SUBMITTER: Royle J
PROVIDER: S-EPMC7290722 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Royle Jamie J Ramírez-Santana Carolina C Akpunarlieva Snezhana S Donald Claire L CL Gestuveo Rommel J RJ Anaya Juan-Manuel JM Merits Andres A Burchmore Richard R Kohl Alain A Varjak Margus M
Viruses 20200509 5
Zika virus (ZIKV; Flaviviridae) is a mosquito-borne flavivirus shown to cause fetal abnormalities collectively known as congenital Zika syndrome and Guillain-Barré syndrome in recent outbreaks. Currently, there is no specific treatment or vaccine available, and more effort is needed to identify cellular factors in the viral life cycle. Here, we investigated interactors of ZIKV envelope (E) protein by combining protein pull-down with mass spectrometry. We found that E interacts with the endoplasm ...[more]