The Role of Gut Dysbiosis in the Bone-Vascular Axis in Chronic Kidney Disease.
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ABSTRACT:
SUBMITTER: Evenepoel P
PROVIDER: S-EPMC7290823 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
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The Role of Gut Dysbiosis in the Bone-Vascular Axis in Chronic Kidney Disease.
Evenepoel Pieter P Dejongh Sander S Verbeke Kristin K Meijers Bjorn B
Toxins 20200429 5
Patients with chronic kidney disease (CKD) are at increased risk of bone mineral density loss and vascular calcification. Bone demineralization and vascular mineralization often concur in CKD, similar to what observed in the general population. This contradictory association is commonly referred to as the 'calcification paradox' or the bone-vascular axis. Mounting evidence indicates that CKD-associated gut dysbiosis may be involved in the pathogenesis of the bone-vascular axis. A disrupted intes ...[more]
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