Ontology highlight
ABSTRACT:
SUBMITTER: De Bartolo MI
PROVIDER: S-EPMC7290883 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
De Bartolo Maria Ilenia MI Manzo Nicoletta N Ferrazzano Gina G Baione Viola V Belvisi Daniele D Fabbrini Giovanni G Berardelli Alfredo A Conte Antonella A
Toxins 20200425 5
(1) Background: In dystonia, the somatosensory temporal discrimination threshold (STDT) is abnormally increased at rest and higher and longer-lasting during movement execution in comparison with healthy subjects (HS), suggesting an abnormal sensorimotor integration. These abnormalities are thought to depend on abnormal proprioceptive input coming from dystonic muscles. Since Botulinum toxin-A (BT-A) reduces proprioceptive input in the injected muscles, our study investigated the effects of BT-A ...[more]