Ontology highlight
ABSTRACT:
SUBMITTER: De Franceschi L
PROVIDER: S-EPMC7291114 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
De Franceschi Lucia L Gabbiani Daniele D Giusti Andrea A Forni Gianluca G Stefanoni Filippo F Pinto Valeria Maria VM Sartori Giulia G Balocco Manuela M Dal Zotto Chiara C Valenti Maria Teresa MT Dalle Carbonare Luca L
Journal of clinical medicine 20200525 5
Sickle-cell disease (SCD) is a worldwide distributed hemoglobinopathy, characterized by hemolytic anemia associated with vaso-occlusive events. These result in acute and chronic multiorgan damage. Bone is early involved, leading to long-term disability, chronic pain and fractures. Here, we carried out a retrospective study to evaluate sickle bone disease (SBD) in a cohort of adults with SCD. We assessed bone density, metabolism and turnover. We also evaluated the presence of fractures and the co ...[more]