Ontology highlight
ABSTRACT:
SUBMITTER: Tsai CH
PROVIDER: S-EPMC7291153 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Tsai Chun-Hao CH Liu Shan-Chi SC Chung Wen-Hui WH Wang Shih-Wei SW Wu Min-Huan MH Tang Chih-Hsin CH
Cells 20200525 5
Osteoarthritis (OA) pannus contains a network of neovascularization that is formed and maintained by angiogenesis, which is promoted by vascular endothelial growth factor (VEGF). Bone marrow-derived endothelial progenitor cells (EPCs) are involved in VEGF-induced vessel formation in OA. The adipokine visfatin stimulates the release of inflammatory cytokines during OA progression. In this study, we found significantly higher visfatin and VEGF serum concentrations in patients with OA compared with ...[more]