Ontology highlight
ABSTRACT: Background
Heterogeneity should be carefully addressed to facilitate establishment of effective population-level blood lipid management. The primary aim of the study was to investigate gender heterogeneity in prevalence of dyslipidemia, including trends with age and associated factors in middle age rural Chinese.Methods
This is a cross-sectional study based on a baseline investigation of a population-based randomized controlled trial in rural China, involving 26,378 permanent residents of age 45-69. The age-specific prevalence of dyslipidemia was estimated for men and women, and the trends of prevalence with age were compared. Logistic regression was used to explore the factors associated with prevalent risk of dyslipidemia.Results
The overall prevalence of dyslipidemia was significantly higher in females than in males for borderline high and above (BHA) total cholesterol (TC???200?mg/dL), BHA triglycerides (TG???150?mg/dL) and BHA low-density lipoprotein cholesterol (LDL-C???130?mg/dL), but was lower for low high-density lipoprotein cholesterol (HDL-C?ConclusionHeterogeneity was found in comparing the prevalence of dyslipidemia in men and women, and gender heterogeneity was found in its trend with age and associated factors in middle aged rural Chinese. The effectiveness of population-level blood lipid management and CVD primary prevention programs in China is expected to be improved if gender heterogeneity is considered.
SUBMITTER: Wang M
PROVIDER: S-EPMC7291723 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Wang Minmin M Liu Mengfei M Li Fenglei F Guo Chuanhai C Liu Zhen Z Pan Yaqi Y Liu Ying Y Liu Fangfang F Cai Hong H Wu Yangfeng Y He Zhonghu Z Ke Yang Y
Lipids in health and disease 20200612 1
<h4>Background</h4>Heterogeneity should be carefully addressed to facilitate establishment of effective population-level blood lipid management. The primary aim of the study was to investigate gender heterogeneity in prevalence of dyslipidemia, including trends with age and associated factors in middle age rural Chinese.<h4>Methods</h4>This is a cross-sectional study based on a baseline investigation of a population-based randomized controlled trial in rural China, involving 26,378 permanent res ...[more]