Ontology highlight
ABSTRACT:
SUBMITTER: Dubiel K
PROVIDER: S-EPMC7293020 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Dubiel Katarzyna K Henry Camille C Spenkelink Lisanne M LM Kozlov Alexander G AG Wood Elizabeth A EA Jergic Slobodan S Dixon Nicholas E NE van Oijen Antoine M AM Cox Michael M MM Lohman Timothy M TM Sandler Steven J SJ Keck James L JL
Nucleic acids research 20200601 11
Bacterial single-stranded DNA-binding proteins (SSBs) bind single-stranded DNA and help to recruit heterologous proteins to their sites of action. SSBs perform these essential functions through a modular structural architecture: the N-terminal domain comprises a DNA binding/tetramerization element whereas the C-terminus forms an intrinsically disordered linker (IDL) capped by a protein-interacting SSB-Ct motif. Here we examine the activities of SSB-IDL fusion proteins in which fluorescent domain ...[more]