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How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?


ABSTRACT: BACKGROUND:Asthma patients experience impairments in health-related quality of life (HRQL). Interventions are available to improve HRQL. EQ-5D-5L is a common generic tool used to evaluate health interventions. However, there is debate over whether the use of this measure is adequate in asthma patients. METHODS:We used data from 371 asthma patients participating in a pulmonary rehabilitation (PR) program from the EPRA randomized controlled trial. We used four time points: T0 randomization, T1 start PR, T2 end PR, T3 3 months follow-up. We calculated floor and ceiling effects, intra-class correlation (ICC), Cohen's d, and regression analysis to measure the sensitivity to changes of EQ-5D-5?L (EQ-5D index and Visual Analog Scale (VAS)) and the disease-specific Asthma Quality of Life Questionnaire (AQLQ). Furthermore, we estimated the minimally important difference (MID). Based on the Asthma Control Test (ACT) scores, we defined three groups: 1. ACT-A (ACT>?19) controlled asthma, 2. ACT-B (14?

SUBMITTER: Szentes BL 

PROVIDER: S-EPMC7293124 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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How does the EQ-5D-5L perform in asthma patients compared with an asthma-specific quality of life questionnaire?

Szentes Boglárka L BL   Schultz Konrad K   Nowak Dennis D   Schuler Michael M   Schwarzkopf Larissa L  

BMC pulmonary medicine 20200613 1


<h4>Background</h4>Asthma patients experience impairments in health-related quality of life (HRQL). Interventions are available to improve HRQL. EQ-5D-5L is a common generic tool used to evaluate health interventions. However, there is debate over whether the use of this measure is adequate in asthma patients.<h4>Methods</h4>We used data from 371 asthma patients participating in a pulmonary rehabilitation (PR) program from the EPRA randomized controlled trial. We used four time points: T0 random  ...[more]

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