Ontology highlight
ABSTRACT:
SUBMITTER: Ma J
PROVIDER: S-EPMC7294119 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Ma Jing J Chen Shiyu S Hao Lili L Sheng Wei W Chen WeiCheng W Ma Xiaojing X Zhang Bowen B Ma Duan D Huang Guoying G
Journal of cellular and molecular medicine 20200505 11
Tetralogy of Fallot (TOF) is the most common complex congenital heart disease (CHD) with uncertain cause. Although long non-coding RNAs (lncRNAs) have been implicated in heart development and several CHDs, their role in TOF is not well understood. This study aimed to investigate how dysregulated lncRNAs contribute to TOF. Using Gene Expression Omnibus data mining, bioinformatics analysis and clinical heart tissue sample detecting, we identified a novel antisense lncRNA TBX5-AS1:2 with unknown fu ...[more]