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The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes.

ABSTRACT: Background:Tea tree oil (TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes (PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells (BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the mRNA levels of the genes involved in the innate immune response of BMECs and PMNL. Results:Our results demonstrated that addition of 0.025% and 0.05% TTO increased the proliferation of BMECs, and significantly enhanced (P

SUBMITTER: Zhan K

PROVIDER: S-EPMC7294674 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes.

Zhan Kang K Yang Tianyu T Feng Baobao B Zhu Xinyu X Chen Yinyin Y Huo Yongjiu Y Zhao Guoqi G

Journal of animal science and biotechnology 20200615

<h4>Background</h4>Tea tree oil (TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes (PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells (BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the mRNA levels of the genes ...[more]

PMID: 32549980

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