Consequences of Folding the Mitochondrial Inner Membrane.
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ABSTRACT:
SUBMITTER: Mannella CA
PROVIDER: S-EPMC7295984 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Consequences of Folding the Mitochondrial Inner Membrane.
Frontiers in physiology 20200609
A fundamental first step in the evolution of eukaryotes was infolding of the chemiosmotic membrane of the endosymbiont. This allowed the proto-eukaryote to amplify ATP generation while constraining the volume dedicated to energy production. In mitochondria, folding of the inner membrane has evolved into a highly regulated process that creates specialized compartments (cristae) tuned to optimize function. Internalizing the inner membrane also presents complications in terms of generating the fold ...[more]
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