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Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy.

ABSTRACT: OBJECTIVES:The different etiology of HF has different prognostic risk factors. Prognosis assessment of ICM and NICM has important clinical value. This study is aimed to explore the predicting factors for ICM and NICM. METHODS:1082 HFrEF patients were retrospectively enrolled from Jan. 01, 2016 to Dec. 31, 2017. On Jan. 31, 2019, 873 patients were enrolled for analysis excluding incomplete, unfollowed, and unexplained data. The patients were divided into ischemic and non-ischemic group. The differences in clinical characteristics and long-term prognosis between the two groups were analyzed, and multivariate Cox analysis was used to predict the respective all-cause mortality, SCD and rehospitalization of CHF. RESULTS:873 patients aged 64(53,73) were divided into two groups: ICM (403, 46.16%) and NICM. At the end, 203 died (111 in ICM, 54.68%), of whom 87 had SCD (53 in ICM, 60.92%) and 269 had rehospitalization for HF(134 in ICM, 49.81%). Independent risk factors affecting all-cause mortality in ICM: DM, previous hospitalization of HF, age, eGFR, LVEF; for SCD: PVB, eGFR, Hb, revascularization; for readmission of HF: low T3 syndrome, PVB, DM, previous hospitalization of HF, eGFR. Otherwise; factors affecting all-cause mortality in NICM: NYHA III-IV, paroxysmal AF/AFL, previous hospitalization of HF, ?-blocker; for SCD: low T3 syndrome, PVB, nitrates, sodium, ?-blocker; for rehospitalization of HF: paroxysmal AF/AFL, previous admission of HF, LVEF. CONCLUSIONS:Both all-cause mortality and SCD in ICM is higher than that in NICM. Different etiologies of CHF have different risk factors affecting the prognosis.

SUBMITTER: Zhang ZH

PROVIDER: S-EPMC7296233 | biostudies-literature | 2020 Mar - Apr

REPOSITORIES: biostudies-literature

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Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy.

Zhang Zhi-Hua ZH Meng Fan-Qi FQ Hou Xiao-Feng XF Qian Zhi-Yong ZY Wang Yao Y Qiu Yuan-Hao YH Jiang Zhe-Yu ZY Du An-Jie AJ Qin Chao-Tong CT Zou Jian-Gang JG

Indian heart journal 20200301 2

<h4>Objectives</h4>The different etiology of HF has different prognostic risk factors. Prognosis assessment of ICM and NICM has important clinical value. This study is aimed to explore the predicting factors for ICM and NICM.<h4>Methods</h4>1082 HFrEF patients were retrospectively enrolled from Jan. 01, 2016 to Dec. 31, 2017. On Jan. 31, 2019, 873 patients were enrolled for analysis excluding incomplete, unfollowed, and unexplained data. The patients were divided into ischemic and non-ischemic g ...[more]

PMID: 32534695

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Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy.

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Clinical characteristics and long-term prognosis of ischemic and non-ischemic cardiomyopathy.

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