Associations of Maternal Prenatal Drug Abuse With Measures of Newborn Brain Structure, Tissue Organization, and Metabolite Concentrations.

ABSTRACT:

Importance

Increasing rates of illicit drug use during pregnancy may be associated with risk for long-term health problems in prenatally exposed children.

Objective

To identify the associations of prenatal exposure to illicit drugs with organization of the newborn brain.

Design, setting, and participants

For this cohort study, a volunteer sample of 210 illicit drug-using and nonusing mothers and their newborns was enrolled from prenatal clinics and drug abuse treatment programs in New York, New York. Enrollment, scanning, and long-term follow-up occurred from September 2004 through February 2012, and image processing and statistical analyses continued through fall 2018. In addition to 26 participants with incomplete data, a total of 64 mothers were lost to follow-up d

SUBMITTER: Peterson BS 

PROVIDER: S-EPMC7296459 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature