Dietary sugar inhibits satiation by decreasing the central processing of sweet taste.
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ABSTRACT:
SUBMITTER: May CE
PROVIDER: S-EPMC7297538 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Dietary sugar inhibits satiation by decreasing the central processing of sweet taste.
May Christina E CE Rosander Julia J Gottfried Jennifer J Dennis Evan E Dus Monica M
eLife 20200616
From humans to vinegar flies, exposure to diets rich in sugar and fat lowers taste sensation, changes food choices, and promotes feeding. However, how these peripheral alterations influence eating is unknown. Here we used the genetically tractable organism <i>D. melanogaster</i> to define the neural mechanisms through which this occurs. We characterized a population of protocerebral anterior medial dopaminergic neurons (PAM DANs) that innervates the β'2 compartment of the mushroom body and respo ...[more]
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