Ontology highlight
ABSTRACT:
SUBMITTER: Hicks DA
PROVIDER: S-EPMC7297870 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
Hicks David A DA Jones Alys C AC Corbett Nicola J NJ Fisher Kate K Pickering-Brown Stuart M SM Ashe Mark P MP Hooper Nigel M NM
Neurochemical research 20200502 7
Healthy brain function is mediated by several complementary signalling pathways, many of which are driven by extracellular vesicles (EVs). EVs are heterogeneous in both size and cargo and are constitutively released from cells into the extracellular milieu. They are subsequently trafficked to recipient cells, whereupon their entry can modify the cellular phenotype. Here, in order to further analyse the mRNA and protein cargo of neuronal EVs, we isolated EVs by size exclusion chromatography from ...[more]