Dataset Information

The differential expression patterns of paralogs in response to stresses indicate expression and sequence divergences.

ABSTRACT:

Background

Theoretically, paralogous genes generated through whole genome duplications should share identical expression levels due to their identical sequences and chromatin environments. However, functional divergences and expression differences have arisen due to selective pressures throughout evolution. A comprehensive investigation of the expression patterns of paralogous gene pairs in response to various stresses and a study of correlations between the expression levels and sequence divergences of the paralogs are needed.

Results

In this study, we analyzed the expression patterns of paralogous genes under different types of stress and investigated the correlations between the expression levels and sequence divergences of the paralogs. We analyzed the differential expression patterns of the paralogs under four different types of stress (drought, cold, infection, and herbivory) and classified them into three main types according to their expression patterns. We then further analyzed the differential expression patterns under various degrees of stress and constructed corresponding co-expression networks of differentially expressed paralogs and transcription factors. Finally, we investigated the correlations between the expression levels and sequence divergences of the paralogs and identified positive correlations between expression level and sequence divergence. With regard to sequence divergence, we identified correlations between selective pressures and phylogenetic relationships.

Conclusions

These results shed light on differential expression patterns of paralogs in response to environmental stresses and are helpful for understanding the relationships between expression levels and sequences divergences.

SUBMITTER: Lian S

PROVIDER: S-EPMC7298774 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature

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Publications

The differential expression patterns of paralogs in response to stresses indicate expression and sequence divergences.

Lian Shuaibin S Zhou Yongjie Y Liu Zixiao Z Gong Andong A Cheng Lin L

BMC plant biology 20200616 1

<h4>Background</h4>Theoretically, paralogous genes generated through whole genome duplications should share identical expression levels due to their identical sequences and chromatin environments. However, functional divergences and expression differences have arisen due to selective pressures throughout evolution. A comprehensive investigation of the expression patterns of paralogous gene pairs in response to various stresses and a study of correlations between the expression levels and sequenc ...[more]

PMID: 32546126

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Dataset Information

The differential expression patterns of paralogs in response to stresses indicate expression and sequence divergences.

Background

Results

Conclusions

Publications

The differential expression patterns of paralogs in response to stresses indicate expression and sequence divergences.

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