Genomic and phenotypic evolution of Escherichia coli in a novel citrate-only resource environment.
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ABSTRACT:
SUBMITTER: Blount ZD
PROVIDER: S-EPMC7299349 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Genomic and phenotypic evolution of <i>Escherichia coli</i> in a novel citrate-only resource environment.
Blount Zachary D ZD Maddamsetti Rohan R Grant Nkrumah A NA Ahmed Sumaya T ST Jagdish Tanush T Baxter Jessica A JA Sommerfeld Brooke A BA Tillman Alice A Moore Jeremy J Slonczewski Joan L JL Barrick Jeffrey E JE Lenski Richard E RE
eLife 20200529
Evolutionary innovations allow populations to colonize new ecological niches. We previously reported that aerobic growth on citrate (Cit<sup>+</sup>) evolved in an <i>Escherichia coli</i> population during adaptation to a minimal glucose medium containing citrate (DM25). Cit<sup>+</sup> variants can also grow in citrate-only medium (DM0), a novel environment for <i>E. coli</i>. To study adaptation to this niche, we founded two sets of Cit<sup>+</sup> populations and evolved them for 2500 generat ...[more]
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