Dataset Information

Data Resource: the Kent Integrated Dataset (KID).

ABSTRACT: Introduction:Electronic healthcare records from the UK are accessible to researchers via several platforms, but these platforms typically include data from a limited subset of health and care services. The Kent Integrated Dataset (KID) provides insight into system-wide health and care utilisation for the whole population of Kent and Medway. Processes:The KID uses pseudonymisation-at-source to link patient-level records from services including general practices, hospitals, community health services and social care. Data is refreshed monthly and processes to monitor data quality have been developed. Data contents:For each episode of care, the KID includes date of the episode, the type of service accessed, the cost of the episode and clinical information such as the health condition being treated and results of diagnostic tests. The dataset also includes contextual information such as the neighbourhood deprivation. Conclusions:The KID is a unique and rich dataset available to researchers who are investigating a broad range of public health questions. It provides system-level insight into patient journeys and care utilisation and supports commissioning based on patient needs.

SUBMITTER: Lewer D

PROVIDER: S-EPMC7299463 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature

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Publications

Data Resource: the Kent Integrated Dataset (KID).

Lewer D D Bourne T T George A A Abi-Aad G G Taylor C C George J J

International journal of population data science 20180425 1

<h4>Introduction</h4>Electronic healthcare records from the UK are accessible to researchers via several platforms, but these platforms typically include data from a limited subset of health and care services. The Kent Integrated Dataset (KID) provides insight into system-wide health and care utilisation for the whole population of Kent and Medway.<h4>Processes</h4>The KID uses pseudonymisation-at-source to link patient-level records from services including general practices, hospitals, communit ...[more]

PMID: 32935003

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Project description:BackgroundThe introduction of high-throughput genome sequencing and post-genome analysis technologies, e.g. DNA microarray approaches, has created the potential to unravel and scrutinize complex gene-regulatory networks on a large scale. The discovery of transcriptional regulatory interactions has become a major topic in modern functional genomics.ResultsTo facilitate the analysis of gene-regulatory networks, we have developed CoryneCenter, a web-based resource for the systematic integration and analysis of genome, transcriptome, and gene regulatory information for prokaryotes, especially corynebacteria. For this purpose, we extended and combined the following systems into a common platform: (1) GenDB, an open source genome annotation system, (2) EMMA, a MAGE compliant application for high-throughput transcriptome data storage and analysis, and (3) CoryneRegNet, an ontology-based data warehouse designed to facilitate the reconstruction and analysis of gene regulatory interactions. We demonstrate the potential of CoryneCenter by means of an application example. Using microarray hybridization data, we compare the gene expression of Corynebacterium glutamicum under acetate and glucose feeding conditions: Known regulatory networks are confirmed, but moreover CoryneCenter points out additional regulatory interactions.ConclusionCoryneCenter provides more than the sum of its parts. Its novel analysis and visualization features significantly simplify the process of obtaining new biological insights into complex regulatory systems. Although the platform currently focusses on corynebacteria, the integrated tools are by no means restricted to these species, and the presented approach offers a general strategy for the analysis and verification of gene regulatory networks. CoryneCenter provides freely accessible projects with the underlying genome annotation, gene expression, and gene regulation data. The system is publicly available at http://www.CoryneCenter.de.

Dataset Information

Data Resource: the Kent Integrated Dataset (KID).

Publications

Data Resource: the Kent Integrated Dataset (KID).

Similar Datasets

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