Ontology highlight
ABSTRACT:
SUBMITTER: Worland AM
PROVIDER: S-EPMC7300164 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Worland Alyssa M AM Czajka Jeffrey J JJ Xing Yun Y Harper Willie F WF Moore Aryiana A Xiao Zhengyang Z Han Zhenlin Z Wang Yechun Y Su Wei Wen WW Tang Yinjie J YJ
Metabolic engineering communications 20200516
This study employs biomass growth analyses and <sup>13</sup>C-isotope tracing to investigate lipid feedstock utilization by <i>Yarrowia lipolytica</i>. Compared to glucose, oil-feedstock in the minimal medium increases the yeast's biomass yields and cell sizes, but decreases its protein content (<20% of total biomass) and enzyme abundances for product synthesis. Labeling results indicate a segregated metabolic network (the glycolysis vs. the TCA cycle) during co-catabolism of sugars (glucose or ...[more]